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beta-2 Microglobulin 抗体

There are 4+ publications for this product available. The 小鼠 单克隆 anti-beta-2 Microglobulin antibody is suitable to detect beta-2 Microglobulin in samples from 小鼠. It has been validated for FACS, IF 和 CyTox.
产品编号 ABIN2688852
发货至: 中国
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Quick Overview for beta-2 Microglobulin 抗体 (ABIN2688852)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

适用

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小鼠

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单克隆

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This beta-2 Microglobulin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Cytotoxicity Test (CyTox)

克隆位点

S19-8
  • 产品特性

    The s19.8 antibody reacts with the b and c alloantigens of β2 microglobulin, originally designated Ly-m11. β2 microglobulin is a 12 kDa protein, homologous to a single immunoglobulin constant-region domain, which is noncovalently associated with the MHC class I heavy chain. It may also associate noncovalently with CD1d in some cells types. Positive strains include C57BL/6, C57BL/10, C57BR, and C57L, whereas, A, AKR, BALB/c, C58, C3H, CBA, DBA/1, DBA/2, SJL, SWR, and 129 strains are negative.

    BD Pharmingen™ Purified Mouse Anti-Mouse β2 Microglobulin[b,c] - Purified - Clone S19.8 - Isotype Mouse IgG2b, κ - Reactivity Ms - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    B10.S Mouse Spleen Cells

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Pérarnau, Saron, Reina San Martin, Bervas, Ong, Soloski, Smith, Ure, Gairin, Lemonnier: "Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses." in: European journal of immunology, Vol. 29, Issue 4, pp. 1243-52, (1999) (PubMed).

    Jullien, Brossay, Sieling, Modlin, Kronenberg: "CD1: clues on a new antigen-presenting pathway." in: Research in immunology, Vol. 147, Issue 5, pp. 321-8, (1997) (PubMed).

    Tada, Kimura, Hatzfeld, Hämmerling: "Ly-m11: the H-3 region of mouse chromosome 2 controls a new surface alloantigen." in: Immunogenetics, Vol. 11, Issue 5, pp. 441-9, (1991) (PubMed).

    Kurtz, Graff, Adelman, Martin-Morgan, Click: "CTL and serologically defined antigens of B2m,H-3 region." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 135, Issue 4, pp. 2847-52, (1985) (PubMed).

  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    Beta2-Microglobulin

    背景

    Synonyms: Ly-m11

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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