beta-2 Microglobulin 抗体
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Quick Overview for beta-2 Microglobulin 抗体 (ABIN2688852)
抗原
See all beta-2 Microglobulin (B2M) 抗体适用
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克隆类型
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应用范围
克隆位点
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产品特性
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The s19.8 antibody reacts with the b and c alloantigens of β2 microglobulin, originally designated Ly-m11. β2 microglobulin is a 12 kDa protein, homologous to a single immunoglobulin constant-region domain, which is noncovalently associated with the MHC class I heavy chain. It may also associate noncovalently with CD1d in some cells types. Positive strains include C57BL/6, C57BL/10, C57BR, and C57L, whereas, A, AKR, BALB/c, C58, C3H, CBA, DBA/1, DBA/2, SJL, SWR, and 129 strains are negative.
BD Pharmingen™ Purified Mouse Anti-Mouse β2 Microglobulin[b,c] - Purified - Clone S19.8 - Isotype Mouse IgG2b, κ - Reactivity Ms - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- B10.S Mouse Spleen Cells
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses." in: European journal of immunology, Vol. 29, Issue 4, pp. 1243-52, (1999) (PubMed).
: "CD1: clues on a new antigen-presenting pathway." in: Research in immunology, Vol. 147, Issue 5, pp. 321-8, (1997) (PubMed).
: "Ly-m11: the H-3 region of mouse chromosome 2 controls a new surface alloantigen." in: Immunogenetics, Vol. 11, Issue 5, pp. 441-9, (1991) (PubMed).
: "CTL and serologically defined antigens of B2m,H-3 region." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 135, Issue 4, pp. 2847-52, (1985) (PubMed).
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: "Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses." in: European journal of immunology, Vol. 29, Issue 4, pp. 1243-52, (1999) (PubMed).
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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别名
- Beta2-Microglobulin
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背景
- Synonyms: Ly-m11
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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