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HIV-1 Tat 抗体 (Biotin)

This anti-HIV-1 Tat antibody is a 兔 多克隆 antibody detecting HIV-1 Tat in WB, ELISA 和 IF. Suitable for Human Immunodeficiency Virus (HIV).
产品编号 ABIN2669357
发货至: 中国

Quick Overview for HIV-1 Tat 抗体 (Biotin) (ABIN2669357)

抗原

See all HIV-1 Tat 抗体
HIV-1 Tat

适用

Human Immunodeficiency Virus (HIV)

宿主

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克隆类型

  • 9
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多克隆

标记

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This HIV-1 Tat antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 特异性

    The antibody detects HIV1 tat protein and GST tat fusion protein. HIVI tat protein in sera or plasma and in cell culture supernatant

    产品特性

    Tat is a regulatory protein of HIV-1 virus, well conserved among different isolates. Tat is produced early after infection and it's essential for virus replication and infectivity. Tat protein is also immunogenic and antibodies (Ab) against tat have been found to correlate with delayed disease progression and may exert protective effects by inhibiting both HIV-1 replication and the effects of extracellular tat. Moreover, tat is efficiently taken up by monocyte-derived dendritic cells, promotes their maturation and antigen presenting since it enters the major histocompatibility complex class I pathway. Finally, murine vaccination with a biologically active tat protein has been shown to be safe, immunogenic and elicits anti-tat neutralizing Ab and CTL.

    纯化方法

    Purified by protein A affinity chromatography and conjugated by NHS-biotin.

    免疫原

    Purified recombinant protein HIV-I tat expressed in E. coli
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied in PBS and 0.05 % v/v glycerol

    储存条件

    4 °C
  • 抗原

    HIV-1 Tat

    别名

    HIV1 Tat

    物质类

    Viral Protein
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