Ubiquitin 抗体
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Quick Overview for Ubiquitin 抗体 (ABIN2668990)
抗原
See all Ubiquitin (Ub) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Ubiquitin antibody (mAb) (Clone P4D1)
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纯化方法
- Protein A Chromatography
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免疫原
- This Ubiquitin antibody was raised against purified bovine ubiquitin.
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亚型
- IgG
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应用备注
- WB For additional information, please see the original publication for the generation of this clone: Kahana, A., and Gottschling, D.E., Mol. Cell. Biol. 19: 6608-6620, 1999. This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91257.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- PBS, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "DOT4 links silencing and cell growth in Saccharomyces cerevisiae." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6608-20, (2000) (PubMed).
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- Ubiquitin (Ub)
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别名
- Ubiquitin
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背景
- Ubiquitin is an important signaling protein that is catalytically added to proteins on lysine residues to modify their function. Addition of multiple ubiquitin proteins in a string (poly-ubiquitylation) to proteins signals their destruction by the proteasome. Mono-ubiquitylation of proteins has a much different effect, more in keeping with post-translational modification of proteins by phosphorylation or acetylation. Mono-ubiquitylation is part of a number of signal transduction pathways, including those involving histone proteins and transcriptional regulation.
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途径
- Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
抗原
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