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Ubiquitin 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-Ubiquitin antibody is suitable to detect Ubiquitin in samples from 人. It has been validated for WB.
产品编号 ABIN2668990
发货至: 中国
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Quick Overview for Ubiquitin 抗体 (ABIN2668990)

抗原

See all Ubiquitin (Ub) 抗体
Ubiquitin (Ub)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Ubiquitin antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

P4D1
  • 原理

    Ubiquitin antibody (mAb) (Clone P4D1)

    纯化方法

    Protein A Chromatography

    免疫原

    This Ubiquitin antibody was raised against purified bovine ubiquitin.

    亚型

    IgG
  • 应用备注

    WB For additional information, please see the original publication for the generation of this clone: Kahana, A., and Gottschling, D.E., Mol. Cell. Biol. 19: 6608-6620, 1999. This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91257.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    PBS, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Kahana, Gottschling: "DOT4 links silencing and cell growth in Saccharomyces cerevisiae." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6608-20, (2000) (PubMed).

  • 抗原

    Ubiquitin (Ub)

    别名

    Ubiquitin

    背景

    Ubiquitin is an important signaling protein that is catalytically added to proteins on lysine residues to modify their function. Addition of multiple ubiquitin proteins in a string (poly-ubiquitylation) to proteins signals their destruction by the proteasome. Mono-ubiquitylation of proteins has a much different effect, more in keeping with post-translational modification of proteins by phosphorylation or acetylation. Mono-ubiquitylation is part of a number of signal transduction pathways, including those involving histone proteins and transcriptional regulation.

    途径

    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
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