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PIWIL2 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-PIWIL2 antibody is suitable to detect PIWIL2 in samples from 小鼠. It has been validated for WB, ICC, IF 和 IP.
产品编号 ABIN2668966
发货至: 中国
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Quick Overview for PIWIL2 抗体 (ABIN2668966)

抗原

See all PIWIL2 抗体
PIWIL2 (Piwi-Like 2 (PIWIL2))

适用

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小鼠

宿主

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小鼠

克隆类型

  • 21
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单克隆

标记

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This PIWIL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

17-8
  • 原理

    Mili / PiwiL2 antibody (mAb) (Clone 17.8)

    纯化方法

    Protein G Chromatography

    免疫原

    This Mili / PiwiL2 antibody was raised against full-length recombinant mouse MILI / PIWIL2 protein.

    亚型

    IgG1
  • 应用备注

    This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91253.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Kirino, Kim, de Planell-Saguer, Khandros, Chiorean, Klein, Rigoutsos, Jongens, Mourelatos: "Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability." in: Nature cell biology, Vol. 11, Issue 5, pp. 652-8, (2009) (PubMed).

  • 抗原

    PIWIL2 (Piwi-Like 2 (PIWIL2))

    别名

    Mili / PiwiL2

    背景

    Mili / PiwiL2 is a member of the PIWI/AGO subfamily of RNA-binding proteins. Mili / PiwiL2 contains a Piwi and an AGO domain and binds a class of RNA called piwi-interacting RNA (piRNA), which are 24 to 30 nucleotides in length and are derived primarily derived from transposons and other repeated sequence elements. Mili / PiwiL2 is required for methylation and inactivation of retrotransposons. Mice deficient in Mili / PiwiL2 are sterile, as it is also required for spermatogenesis. It also positively regulates translation, and is required for germ line stem cell division and differentiation.

    分子量

    97 kDa

    基因ID

    57746

    NCBI登录号

    NP_001129193

    途径

    Stem Cell Maintenance
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