SUZ12 抗体
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北京 101111
Quick Overview for SUZ12 抗体 (ABIN2668948)
抗原
See all SUZ12 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Suz12 antibody (mAb) (Clone 2AO9)
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纯化方法
- Protein G Chromatography
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免疫原
- This Suz12 antibody was raised against a recombinant protein corresponding to full-length human Suz12.
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亚型
- IgG2b
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anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) antibody
SUZ12 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) (AA 1-139) antibodySUZ12 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2B9G12 unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) (AA 470-739) antibodySUZ12 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) (C-Term) antibodySUZ12 适用: 人, 小鼠 WB, IF, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) antibodySUZ12 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) antibodySUZ12 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 1B10 unconjugated Recombinant Antibody
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) (AA 131-305) antibodySUZ12 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) (AA 381-395) antibodySUZ12 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52373 unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) (AA 362-411) antibodySUZ12 适用: 人, 小鼠, Cow, 犬, 马, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) (AA 559-588), (C-Term) antibodySUZ12 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB42757 unconjugated
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应用备注
- ChIP: 2.5 - 10 μg per ChIP This antibody has been published, but has not been validated by Active Motif, for Western blot. For an antibody validated for use in Western blotting, see Catalog No. 39357. This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91163.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2." in: Genes & development, Vol. 22, Issue 10, pp. 1345-55, (2008) (PubMed).
: "Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor." in: Molecular and cellular biology, Vol. 28, Issue 15, pp. 4772-81, (2008) (PubMed).
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- SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
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别名
- Suz12
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背景
- Suz12 (Suppressor-of-Zeste 12 protein, also designated as ChET9, JJAZ1 protein) is a component of the Polycomb group complexes 2, 3 and 4 (PRC2, PRC3 and PRC4), which also contain the histone methyltransferase EZH2, EED (Embryonic Ectoderm Development protein) protein and the histone-binding proteins RbAP46 and RbAP48. PRC2 is responsible for di- and trimethylation of histone 3 at lysine 27 (Histone H3K27me2 and Histone H3K27me3), which leads to transcriptional repression of the target genes. Suz12 is a nuclear protein belonging to the VEFS family. Suz12 contains a zinc-finger binding motif and a VEFS box, which is required for the interaction between Suz12 and EZH2.
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分子量
- 95 kDa
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基因ID
- 23512
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NCBI登录号
- NP_056170
抗原
-
