PRDM1 抗体
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北京 101111
Quick Overview for PRDM1 抗体 (ABIN2668849)
抗原
See all PRDM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PRDM1 / BLIMP1 antibody (mAb) (Clone ROS195)
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纯化方法
- Protein G Chromatography
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免疫原
- This PRDM1 / BLIMP1 antibody was raised against full-length recombinant human PRDM1 / BLIMP1 protein.
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亚型
- IgG1
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anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 1-109) antibody
PRDM1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (Internal Region) antibodyVerified PRDM1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 690-825) antibodyPRDM1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F1B6 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 1-109) antibodyPRDM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 422-493) antibodyPRDM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 690-825) antibodyPRDM1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 7C11H1 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (C-Term) antibodyVerified PRDM1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 29-149) antibodyPRDM1 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 1-789) antibodyPRDM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 422-493) antibodyPRDM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A3 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas." in: The American journal of pathology, Vol. 173, Issue 1, pp. 242-52, (2008) (PubMed).
: "PRDM1 is involved in chemoresistance of T-cell lymphoma and down-regulated by the proteasome inhibitor." in: Blood, Vol. 111, Issue 7, pp. 3867-71, (2008) (PubMed).
: "Rituximab plus CHOP (R-CHOP) overcomes PRDM1-associated resistance to chemotherapy in patients with diffuse large B-cell lymphoma." in: Blood, Vol. 110, Issue 1, pp. 339-44, (2007) (PubMed).
: "PRDM1/BLIMP-1 expression in multiple B and T-cell lymphoma." in: Haematologica, Vol. 91, Issue 4, pp. 467-74, (2006) (PubMed).
: "[Malignant fibrous histiocytoma of soft tissues: early report of 10 cases]." in: Medicina clínica, Vol. 97, Issue 7, pp. 279, (1991) (PubMed).
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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别名
- PRDM1 / BLIMP1
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背景
- PRDM1 / BLIMP1 is a transcriptional repressor that binds to specific target sites in DNA and recruits co-repressors. PRDM1 / BLIMP1 is a master regulator for B cell terminal differentiation, is essential for normal development and immunity and a putative tumor suppressor in diffuse large B cell lymphomas (DLBCLs). PRDM1 / BLIMP1 specifies primordial germ cells through the silencing of the default somatic pathway. PRDM1 / BLIMP1 also acts as a master regulator of intestinal maturation.
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分子量
- 77 & 95 kDa
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基因ID
- 639
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NCBI登录号
- NP_001189
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途径
- Regulation of Muscle Cell Differentiation
抗原
-
