SRF 抗体
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北京 101111
Quick Overview for SRF 抗体 (ABIN2668813)
抗原
See all SRF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SRF antibody (mAb) (Clone 2C5)
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纯化方法
- Protein G Chromatography
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免疫原
- This antibody was raised against a full-length protein corresponding to mouse SRF.
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亚型
- IgG2a
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anti-Serum Response Factor (SRF) (AA 154-508) antibody
SRF 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Serum Response Factor (SRF) (AA 101-250) antibodySRF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serum Response Factor (SRF) (AA 406-508) antibodySRF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Serum Response Factor (SRF) (pSer99) antibodySRF 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Serum Response Factor (SRF) (AA 25-75) antibodySRF 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Monoclonal BLR308M unconjugated Recombinant Antibody
anti-Serum Response Factor (SRF) (AA 25-75) antibodySRF 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Monoclonal BLR308M unconjugated Recombinant Antibody
anti-Serum Response Factor (SRF) (AA 406-508) antibodySRF 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Serum Response Factor (SRF) (N-Term) antibodySRF 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Serum Response Factor (SRF) (AA 57-269) antibodySRF 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Serum Response Factor (SRF) (pSer77) antibodySRF 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- ChIP: 5 - 10 µL per ChIP ChIP-Seq: 5 - 10 µL each ChIP-Seq validation was performed by Active Motif's Epigenetics Services, the complete data set is available in the UCSC Genome Browser by clicking here.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase." in: Cardiovascular research, Vol. 104, Issue 1, pp. 15-23, (2014) (PubMed).
: "Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice." in: The Journal of clinical investigation, Vol. 119, Issue 4, pp. 899-910, (2009) (PubMed).
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- SRF (Serum Response Factor (SRF))
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别名
- SRF
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背景
- SRF (serum response factor) is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
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分子量
- 67 kDa
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基因ID
- 20807
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NCBI登录号
- NP_065239
抗原
-
