CARM1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for CARM1 抗体 (C-Term) (ABIN2668761)
抗原
See all CARM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- CARM1 antibody (pAb)
-
纯化方法
- Unpurified
-
免疫原
- This CARM1 antibody was raised against a peptide corresponding to the C-terminus of mouse CARM1.
-
-
-
-
应用备注
- WB: 1:250 - 1:1,000 dilution The addition of 0.05 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
-
储存条件
- -20 °C
-
储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
有效期
- 24 months
-
-
-
: "PELP1 oncogenic functions involve CARM1 regulation." in: Carcinogenesis, Vol. 34, Issue 7, pp. 1468-75, (2013) (PubMed).
-
-
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
-
别名
- CARM1
-
背景
- CARM1 (Coactivator-associated arginine methyltransferase 1 or CARM 1) is a protein arginine N-methyltransferase that catalyzes the mono- and asymmetric dimethylation of arginine residues in its substrate proteins. It serves as a coactivator of transcription and also plays a role in nuclear receptors. CARM1 methylates histone H3 at Arg2, Arg17 and Arg26, it also methylates a number of non-histone substrates involved in the regulation and mechanism of gene expression.
-
分子量
- 60 kDa
-
基因ID
- 10498
-
NCBI登录号
- NP_067506
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
-