EED 抗体
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北京 101111
Quick Overview for EED 抗体 (ABIN2668749)
抗原
See all EED 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- EED antibody (mAb) (Clone 41D)
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纯化方法
- Protein A Chromatography
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免疫原
- This EED antibody was raised against full-length recombinant human EED protein.
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亚型
- IgG2a
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应用备注
- ChIP: 4 µL per ChIP ChIP-Seq: 4 µL each IHC: 2 - 8 μg/mL dilution This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91135.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- EED (Embryonic Ectoderm Development (EED))
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别名
- EED
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背景
- EED (extraembryonic ectoderm) is a component of the Polycomb group (PcG) multiprotein complex PRC2. The PRC2 complex also contains EZH2 and SUZ12 and is recruited to Polycomb response elements and results in the methylation of histone H3 and lysine 27 and the silencing of gene expression. PRC2 initiates repression of the Hox genes during development and is involved in the maintenance of stem cell pluripotency. EED is a member of the superfamily of WD-40 repeat protein family and is required for PRC2-mediated H3K27 methylation. The PRC2 complex may also recruit platform DNMTs, thereby linking two systems of epigenetic repression.
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分子量
- 57 kDa
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基因ID
- 8726
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NCBI登录号
- NP_003788
抗原
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