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Retinoic Acid Receptor gamma 抗体 (AA 428-441)

Cited in 2+ publications. The 小鼠 单克隆 anti-Retinoic Acid Receptor gamma antibody (Clone 4gamma-7A11) (ABIN2668712) specifically detects Retinoic Acid Receptor gamma in WB, IHC 和 SSA. The antibody is reactive with 人 samples.
产品编号 ABIN2668712
发货至: 中国
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Quick Overview for Retinoic Acid Receptor gamma 抗体 (AA 428-441) (ABIN2668712)

抗原

See all Retinoic Acid Receptor gamma (RARG) 抗体
Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Retinoic Acid Receptor gamma antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Supershift Assay (SSA)

克隆位点

4gamma-7A11
  • 抗原表位

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    AA 428-441

    原理

    RAR-gamma antibody (mAb) (Clone 4g-7A11)

    纯化方法

    Protein G Chromatography

    免疫原

    This RAR-g antibody was raised against a recombinant protein corresponding to amino acids 428-441 (F-region) of human RARg.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Hoftijzer, Liu, Morreau, van Wezel, Pereira, Corssmit, Romijn, Smit: "Retinoic acid receptor and retinoid X receptor subtype expression for the differential diagnosis of thyroid neoplasms." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 160, Issue 4, pp. 631-8, (2009) (PubMed).

    Reichrath, Mittmann, Kamradt, Müller: "Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin: an immunohistological evaluation." in: The Histochemical journal, Vol. 29, Issue 2, pp. 127-33, (1997) (PubMed).

  • 抗原

    Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

    别名

    RAR-gamma

    背景

    Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-g has two splice isoforms. RAR-g heterodimerizes with RXR and in the absence of ligand, the RAR/RXR dimer binds to hormone response elements complexed with co-repressor protein. Binding of agonist ligands to RAR results in dissociation of co-repressor and recruitment of coactivator protein which in turn promotes transcription of the downstream target gene into mRNA and eventually protein.

    分子量

    52 kDa

    基因ID

    5916

    NCBI登录号

    NP_000957

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size
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