Retinoic Acid Receptor alpha 抗体 (AA 420-443)
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北京 101111
Quick Overview for Retinoic Acid Receptor alpha 抗体 (AA 420-443) (ABIN2668711)
抗原
See all Retinoic Acid Receptor alpha (RARA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 420-443
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原理
- RAR-alpha antibody (mAb) (Clone 9a-9A6)
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纯化方法
- Protein A Chromatography
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免疫原
- This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.
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亚型
- IgG1 kappa
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anti-Retinoic Acid Receptor, alpha (RARA) (AA 68-173) antibody
RARA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 322-349), (C-Term) antibodyRARA 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33783 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 1-457) antibodyRARA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 237-459) antibodyRARA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 1-462) antibodyRARA 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C9-1F8 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (N-Term) antibodyRARA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (C-Term) antibodyVerified RARA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.71 μg/μL
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缓冲液
- Purified IgG in 60 mM Sodium Citrate, 105 mM Tris-HCl, 30 % glycerol, and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Pharmacogenomic analysis of acute promyelocytic leukemia cells highlights CYP26 cytochrome metabolism in differential all-trans retinoic acid sensitivity." in: Blood, Vol. 109, Issue 10, pp. 4450-60, (2007) (PubMed).
: "Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin: an immunohistological evaluation." in: The Histochemical journal, Vol. 29, Issue 2, pp. 127-33, (1997) (PubMed).
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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别名
- RAR-alpha
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背景
- Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-a (Nuclear receptor subfamily 1 group B member 1, NR1B1) interacts with NCoA3, NCoA6, NCoA7 and MLL to activate transcription of target genes. Chromosomal aberrations of RAR-a are sometimes involved in Promyelocytic leukemia.
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分子量
- 52 kDa
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基因ID
- 5914
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NCBI登录号
- NP_001138773
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
抗原
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