SUV39H1 抗体 (AA 1-126)
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北京 101111
Quick Overview for SUV39H1 抗体 (AA 1-126) (ABIN2668694)
抗原
See all SUV39H1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-126
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原理
- SUV39H1 antibody (mAb) (Clone MG44)
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纯化方法
- Protein G Chromatography
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免疫原
- This SUV39H1 antibody was raised against a recombinant protein corresponding to amino acids 1-126 of mouse SUV39H1.
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亚型
- IgG1
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anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) antibody
SUV39H1 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (C-Term) antibodySUV39H1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (N-Term) antibodySUV39H1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2153 unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 179-412) antibodySUV39H1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 1-220) antibodySUV39H1 适用: 人 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (C-Term) antibodySUV39H1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (C-Term) antibodySUV39H1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 108-157) antibodySUV39H1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (N-Term) antibodySUV39H1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 79-108) antibodySUV39H1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Epidermal growth factor receptor regulates beta-catenin location, stability, and transcriptional activity in oral cancer." in: Molecular cancer, Vol. 9, pp. 64, (2010) (PubMed).
: "On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin." in: RNA (New York, N.Y.), Vol. 14, Issue 9, pp. 1773-81, (2008) (PubMed).
: "Aurora-B/AIM-1 regulates the dynamic behavior of HP1alpha at the G2-M transition." in: Molecular biology of the cell, Vol. 17, Issue 7, pp. 3232-41, (2006) (PubMed).
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- SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
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别名
- SUV39H1
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背景
- SUV39H1 is one of two homologues of the Drosophila Suppressor-of-variegation 3(9) protein (aka Su(var)3-9). SUV39H1 is a SET domain-containing histone methyltransferase specific for lysine 9 of histone H3. Lysine 9 methylation of histone H3 is found at regions of the genome that are transcriptionally silenced, such as centromeres, repetitive elements and inactive genes. H3 lysine 9 methylation is a hallmark of heterochromatin, regions of the genome that are in a tightly compacted state and relatively devoid of gene expression. HP1 proteins recognize and bind lysine 9 methylation and this contributes to maintaining heterochromatin in its compact and inactive state. SUV39H1 also contains a chromodomain, which may bind to lysine 9 methylation and contribute to the regional spreading of lysine 9 methylation and the establishment of heterochromatin over broader domains of the genome.
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分子量
- 50 kDa
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基因ID
- 6839
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NCBI登录号
- NP_035644
抗原
-
