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ESRRA 抗体 (C-Term)

The 兔 多克隆 anti-ESRRA antibody (ABIN2668679) specifically detects ESRRA in WB. The antibody is reactive with 人 samples.
产品编号 ABIN2668679
发货至: 中国
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Quick Overview for ESRRA 抗体 (C-Term) (ABIN2668679)

抗原

See all ESRRA 抗体
ESRRA (Estrogen-Related Receptor alpha (ESRRA))

适用

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宿主

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克隆类型

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多克隆

标记

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This ESRRA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    ERR-a antibody (pAb)

    纯化方法

    Affinity Purified

    免疫原

    This ERR-alpha antibody was raised against a peptide within the C-terminal region of human ERR alpha.

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:1,000 dilution

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    ESRRA (Estrogen-Related Receptor alpha (ESRRA))

    别名

    ERR-alpha

    背景

    ERR-a (Estrogen-related receptor alpha, NR3B1) is an orphan nuclear receptor similar to the Estrogen Receptor. It is a sequence-specific DNA binding transcriptional activator that is constitutively active in the absence of ligand binding. No true physiological ligands have been found, but estrogen-like compounds from plants have been shown to activate ERR-a. ERR-a and ER-a have been found to regulate an overlapping set of genes, and ERR-a appears to modulate the activity of ER-a in some tissue types. ERR-a regulates genes involved in mitochondrial biogenesis, gluconeogenesis, oxidative phosphorylation, and fatty acid metabolism. ERR-a knockout mice display impaired fat metabolism and absorption.

    分子量

    50 kDa

    基因ID

    2101

    NCBI登录号

    NP_004442

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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