ESRRA 抗体 (C-Term)
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Quick Overview for ESRRA 抗体 (C-Term) (ABIN2668679)
抗原
See all ESRRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- ERR-a antibody (pAb)
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纯化方法
- Affinity Purified
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免疫原
- This ERR-alpha antibody was raised against a peptide within the C-terminal region of human ERR alpha.
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:1,000 dilution
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- ESRRA (Estrogen-Related Receptor alpha (ESRRA))
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别名
- ERR-alpha
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背景
- ERR-a (Estrogen-related receptor alpha, NR3B1) is an orphan nuclear receptor similar to the Estrogen Receptor. It is a sequence-specific DNA binding transcriptional activator that is constitutively active in the absence of ligand binding. No true physiological ligands have been found, but estrogen-like compounds from plants have been shown to activate ERR-a. ERR-a and ER-a have been found to regulate an overlapping set of genes, and ERR-a appears to modulate the activity of ER-a in some tissue types. ERR-a regulates genes involved in mitochondrial biogenesis, gluconeogenesis, oxidative phosphorylation, and fatty acid metabolism. ERR-a knockout mice display impaired fat metabolism and absorption.
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分子量
- 50 kDa
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基因ID
- 2101
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NCBI登录号
- NP_004442
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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