SOX2 抗体 (AA 111-140)
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北京 101111
Quick Overview for SOX2 抗体 (AA 111-140) (ABIN2668593)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-140
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原理
- Sox2 antibody (pAb)
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纯化方法
- Unpurified
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免疫原
- This Sox2 antibody was raised against a peptide corresponding to amino acids amino acids 111-140 mouse Sox2.
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anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
KO Validated SOX2 适用: 人 WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibodySOX2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal SOX2-1791 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibodySOX2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibodySOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, Pig, 绵羊, 斑马鱼, 犬, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibodySOX2 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 10F10 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibodySOX2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, 绵羊, 斑马鱼, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (C-Term) antibodySOX2 适用: 人, 小鼠 WB, IF, ICC, ChIP-seq, ChIP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2,000 - 1:10,000 dilution
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice." in: Scientific reports, Vol. 6, pp. 28238, (2016) (PubMed).
: "A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness." in: Nucleic acids research, Vol. 44, Issue 22, pp. 10603-10618, (2016) (PubMed).
: "The overexpression of SOX2 affects the migration of human teratocarcinoma cell line NT2/D1." in: Anais da Academia Brasileira de Ciências, Vol. 87, Issue 1, pp. 389-404, (2015) (PubMed).
: "Cellular distribution of Egr1 transcription in the male rat pituitary gland." in: Journal of molecular endocrinology, Vol. 53, Issue 2, pp. 271-80, (2014) (PubMed).
: "Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage." in: Molecular and cellular biology, Vol. 31, Issue 22, pp. 4593-608, (2011) (PubMed).
: "Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells." in: PLoS ONE, Vol. 4, Issue 12, pp. e8248, (2009) (PubMed).
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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别名
- Sox2
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背景
- Sox2 (SRY related HMG BOX gene 2) is a DNA binding transcription factor and a member of the SOX family of proteins. SOX proteins have an HMG box that binds DNA. Sox2 forms a complex with Oct-4 and controls the expression of a number of genes involved in embryonic. Sox2 is critical for early embryogenesis and for embryonic stem cell pluripotency and thus can serve as a stem cell marker. Overexpression of Sox2 (along with Oct-4, KLF4 and c-Myc) can transform mouse fibroblasts into a state resembling embryonic stem cells (ES cells), referred to as Induced Pluripotency. Defects in Sox2 are the cause of microphthalmia syndromic type 3.
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分子量
- 35 kDa
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基因ID
- 6657
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NCBI登录号
- NP_035573
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途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
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