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DDIT3 抗体

There are 2+ publications for this product available. The 小鼠 单克隆 anti-DDIT3 antibody is suitable to detect DDIT3 in samples from 小鼠. It has been validated for WB 和 IP.
产品编号 ABIN2668558
发货至: 中国
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Quick Overview for DDIT3 抗体 (ABIN2668558)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

9C8
  • 原理

    Ddit3 antibody (mAb) (Clone 9C8)

    纯化方法

    Protein G Chromatography

    免疫原

    This antibody was raised against full-length recombinant mouse Ddit3 protein.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Kuroda, Wang, Sok, Yin, Chung, Giannotti, Jacobs, Fitz, Murtha-Riel, Turner, Ron: "Induction of a secreted protein by the myxoid liposarcoma oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 5025-30, (1999) (PubMed).

    Wang, Kuroda, Sok, Batchvarova, Kimmel, Chung, Zinszner, Ron: "Identification of novel stress-induced genes downstream of chop." in: The EMBO journal, Vol. 17, Issue 13, pp. 3619-30, (1998) (PubMed).

  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    Ddit3

    背景

    Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.

    分子量

    29 kDa

    基因ID

    13198

    NCBI登录号

    NP_031863

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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