DDIT3 抗体
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北京 101111
Quick Overview for DDIT3 抗体 (ABIN2668558)
抗原
See all DDIT3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Ddit3 antibody (mAb) (Clone 9C8)
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纯化方法
- Protein G Chromatography
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免疫原
- This antibody was raised against full-length recombinant mouse Ddit3 protein.
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Induction of a secreted protein by the myxoid liposarcoma oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 5025-30, (1999) (PubMed).
: "Identification of novel stress-induced genes downstream of chop." in: The EMBO journal, Vol. 17, Issue 13, pp. 3619-30, (1998) (PubMed).
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- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
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别名
- Ddit3
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背景
- Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.
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分子量
- 29 kDa
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基因ID
- 13198
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NCBI登录号
- NP_031863
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途径
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
抗原
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