CHD2 抗体 (C-Term)
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Quick Overview for CHD2 抗体 (C-Term) (ABIN2667961)
抗原
See all CHD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- CHD2 antibody (pAb)
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纯化方法
- Affinity Purified
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免疫原
- This CHD2 antibody (pAb) was raised against a peptide corresponding to the C-terminus of human CHD2.
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亚型
- IgG
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应用备注
- WB: 1:250 - 1:1,000 dilution The addition of 0.1 % Tween 20 in all blocking solutions may reduce background. Individual optimization may be required.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- CHD2 (Chromodomain Helicase DNA Binding Protein 2 (CHD2))
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别名
- CHD2
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背景
- CHD (Chromo-ATPase/Helicase-DNA-binding) proteins, which are ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation, are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD2 is required for normal development of mouse embryos.
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分子量
- 260 kDa
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基因ID
- 1106
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NCBI登录号
- NP_001262
抗原
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