TET3 抗体 (AA 1159-1329)
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Quick Overview for TET3 抗体 (AA 1159-1329) (ABIN2668513)
抗原
See all TET3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1159-1329
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原理
- Tet3 antibody (pAb)
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纯化方法
- Unpurified
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免疫原
- This antibody was raised against a recombinant protein corresponding to amino acids 1159-1329 of mouse Tet3.
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anti-Tet Methylcytosine Dioxygenase 3 (TET3) (AA 1525-1660) antibody
TET3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 3 (TET3) (AA 72-335) antibodyTET3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 3 (TET3) (AA 1-937) antibodyTET3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1,000 - 1:5,000 dilution
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))
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别名
- Tet3
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背景
- Tet3 (tet methylcytosine dioxygenase 3) catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC) and plays a key role in epigenetic chromatin reprogramming in the zygote following fertilization. Conversion into 5hmC initiates a process leading to cytosine demethylation through deamination into 5-hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in DNA demethylation in the paternal pronucleus by mediating conversion of 5mC into 5hmC.
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分子量
- 200 kDa
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基因ID
- 194388
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NCBI登录号
- NP_898961
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途径
- Warburg Effect
抗原
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