SIP1 抗体 (AA 1-360)
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Quick Overview for SIP1 抗体 (AA 1-360) (ABIN2668496)
抗原
See all SIP1 (GEMIN2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-360
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原理
- SIP1 antibody (mAb) (Clone 6E5)
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纯化方法
- Protein G Chromatography
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免疫原
- This SIP1 antibody was raised against a recombinant protein corresponding to amino acids 1-360 of human SIP1.
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亚型
- IgG2a
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anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) antibody
KD Validated GEMIN2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5835 unconjugated Recombinant Antibody
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (C-Term) antibodyGEMIN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) antibodyGEMIN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) antibodyGEMIN2 适用: 人 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) antibodyGEMIN2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 12-280) antibodyGEMIN2 适用: 人, 小鼠, 非洲爪蟾 WB, ELISA, IF, ICC, IP, FACS 宿主: 小鼠 Monoclonal 2E17 unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 51-150) antibodyGEMIN2 适用: 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (Middle Region) antibodyGEMIN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (N-Term) antibodyGEMIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 35-84) antibodyGEMIN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig, 豚鼠, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1 - 4 μg/mL dilution
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma." in: Genes & cancer, Vol. 4, Issue 11-12, pp. 486-500, (2014) (PubMed).
: "JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines." in: PLoS ONE, Vol. 9, Issue 12, pp. e115684, (2014) (PubMed).
: "Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays." in: Experimental and molecular pathology, Vol. 89, Issue 2, pp. 182-9, (2010) (PubMed).
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- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
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别名
- SIP1
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背景
- SIP1 (Smad-interacting protein 1, aka ZEB2, Zinc finger E-box-binding homeobox 2) is a sequence-specific DNA binding protein and transcriptional repressor that is involved in normal embryonic development of neural structures and the neural crest. SIP1 belongs to the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins and contains a SMAD-binding domain, a homeodomain and two clusters of zinc fingers on the N- and C-termini. SIP1 interacts directly with activated forms of SMAD1, SMAD2 and SMAD3, as well as CBX4 and CTBP1. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR).
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分子量
- 180 kDa
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基因ID
- 8487
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NCBI登录号
- NP_055610
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途径
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
抗原
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