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MLL/KMT2A 抗体 (AA 2829-2883)

This anti-MLL/KMT2A antibody is a 兔 多克隆 antibody detecting MLL/KMT2A in WB, ChIP, ICC, ChIP-seq 和 IF. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN2668494
发货至: 中国

Quick Overview for MLL/KMT2A 抗体 (AA 2829-2883) (ABIN2668494)

抗原

See all MLL/KMT2A (MLL) 抗体
MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

适用

  • 26
  • 11
  • 9
人, 小鼠

宿主

  • 19
  • 7

克隆类型

  • 20
  • 6
多克隆

标记

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MLL/KMT2A antibody is un-conjugated

应用范围

  • 10
  • 9
  • 9
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq), Immunofluorescence (IF)
  • 抗原表位

    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2829-2883

    纯化方法

    Protein A Chromatography

    免疫原

    This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件

    -20 °C

    储存方法

    Antibodies in solution can be stored at -20 °C for 2 years.

    有效期

    6 months
  • Kühn, Löscher, Marschalek: "The IRX1/HOXA connection: insights into a novel t(4;11)- specific cancer mechanism." in: Oncotarget, Vol. 7, Issue 23, pp. 35341-52, (2016) (PubMed).

    Kang, Piao, Ryu, Kang, Chang, Keum, Hyun: "Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells." in: Oncotarget, Vol. 7, Issue 26, pp. 40594-40620, (2016) (PubMed).

    Ahmad, Katryniok, Scholz, Merkens, Löscher, Marschalek, Steinhilber: "Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL." in: Oncogenesis, Vol. 3, pp. e127, (2014) (PubMed).

    Pradeepa, Grimes, Taylor, Sutherland, Bickmore: "Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins." in: Nucleic acids research, Vol. 42, Issue 14, pp. 9021-32, (2014) (PubMed).

    Wilkinson, Ballabio, Geng, North, Tapia, Kerry, Biswas, Roeder, Allis, Melnick, de Bruijn, Milne: "RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction." in: Cell reports, Vol. 3, Issue 1, pp. 116-27, (2013) (PubMed).

  • 抗原

    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

    别名

    MLL / HRX

    分子量

    180 kDa

    基因ID

    4297

    途径

    Warburg Effect
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