Histone H3.X/Y 抗体
Cited in 1 publication.
The 大鼠 单克隆 anti-Histone H3.X/Y antibody (Clone 8H6-2111) (ABIN2668484) specifically detects Histone H3.X/Y in ChIP, ICC, IF 和 WB.
The antibody is reactive with 人 samples.
(1 reference)
产品编号 ABIN2668484
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Histone H3.X/Y 抗体 (ABIN2668484)
抗原
Histone H3.X/Y
适用
人
宿主
大鼠
克隆类型
单克隆
应用范围
Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
克隆位点
8H6-2111
-
-
原理
- Histone H3.X/Y antibody (mAb) (Clone 8H6-2111)
-
纯化方法
- Protein G Chromatography
-
免疫原
- This H3.X/Y antibody was raised against a synthetic peptide corresponding to amino acids 9 - 20 of human H3.X.
-
亚型
- IgG2a
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1 μg/μL
-
缓冲液
- Purified rat IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
-
储存条件
- -20 °C
-
储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
有效期
- 24 months
-
-
-
: "Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y." in: The Journal of cell biology, Vol. 190, Issue 5, pp. 777-91, (2010) (PubMed).
-
-
- Histone H3.X/Y
-
背景
- Histones H3.X and H3.Y are primate-specific variants of histone H3. H3.X and H3.Y are roughly 80 % conserved compared to histone H3.3 The H3.Y protein is highly expressed in several primary cell lines, cancer cell lines and human brain. Expression of histone H3.Y is induced by stress. Exogenously expressed H3.X and H3.Y are efficiently incorporated into chromatin and exhibit dynamics similar to canonical histone H3. Knockdown of H3.Y results in slowed growth and altered expression of cell cycle related genes.
-
分子量
- 17 kDa
-
基因ID
- 440093
抗原
-
You are here:
