CENPA 抗体 (pSer18)
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北京 101111
Quick Overview for CENPA 抗体 (pSer18) (ABIN2668362)
抗原
See all CENPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer18
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原理
- CENP-A phospho Ser18 antibody (pAb)
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纯化方法
- Affinity Purified
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免疫原
- This antibody was raised against a synthetic peptide containing phosphorylated serine 16 and 18 of human CENP-A.
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亚型
- IgG
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anti-Centromere Protein A (CENPA) (pSer16), (pSer18) antibody
CENPA 适用: 人 WB, IF, ICC, DB 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein A (CENPA) (N-Term) antibodyCENPA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein A (CENPA) antibody (Atto 488)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 Atto 488
anti-Centromere Protein A (CENPA) antibody (Atto 594)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 Atto 594
anti-Centromere Protein A (CENPA) antibody (Atto 390)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 Atto 390
anti-Centromere Protein A (CENPA) antibody (APC)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 APC
anti-Centromere Protein A (CENPA) antibody (FITC)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 FITC
anti-Centromere Protein A (CENPA) antibody (Biotin)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 Biotin
anti-Centromere Protein A (CENPA) antibody (HRP)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 HRP
anti-Centromere Protein A (CENPA) antibody (PE)CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 PE
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应用备注
- ICC/IF: 1:100 dilution WB: 1:100 - 1:500 dilution The addition of 0.05 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Both tails and the centromere targeting domain of CENP-A are required for centromere establishment." in: The Journal of cell biology, Vol. 208, Issue 5, pp. 521-31, (2015) (PubMed).
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- CENPA (Centromere Protein A (CENPA))
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别名
- CENP-A
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背景
- CENP-A (Centromere Protein A) is a Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. It is required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. Recently, phosphorylation of CENP-A on Ser16 and Ser18 was reported and found to be important for chromosome segregation during mitosis.
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分子量
- 16 kDa
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基因ID
- 1058
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NCBI登录号
- NP_001800
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途径
- Chromatin Binding, Maintenance of Protein Location
抗原
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