Histone H2A, H4 (H4S1ph) 抗体
The 兔 多克隆 anti-Histone H2A, H4 antibody is suitable to detect Histone H2A, H4 in samples from 人. It has been validated for WB 和 DB.
产品编号 ABIN2668297
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Histone H2A, H4 (H4S1ph) 抗体 (ABIN2668297)
抗原
Histone H2A, H4
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Dot Blot (DB)
-
-
抗原表位
- H4S1ph
-
原理
- Histone H2A/H4S1ph antibody (pAb)
-
纯化方法
- Unpurified
-
免疫原
- This Histone H2A/H4 phospho Ser1 antibody was raised against a peptide including phospho-serine 1 of human histone H2A.
-
-
anti-Histone H2A, H4 (H2AS1ph), (H4S1ph) antibody
适用: Various Species WB, ELISA, ICC 宿主: 兔 Monoclonal RM216 unconjugated Recombinant Antibody
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
-
储存条件
- -20 °C
-
储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
有效期
- 24 months
-
-
- Histone H2A, H4
-
别名
- Histone H2A/H4
-
背景
- Histones H2A and H4 are core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression. The first five amino acids of histone H2A and histone H4 are identical in metazoans and include an amino-terminal serine residue. Histone H2A phosphorylation at serine 1 is enriched during mitosis, while H4 phosphorylation increases subsequent to DNA double-strand breaks.
-
分子量
- 14 and 8 kDa
-
基因ID
- 92815
抗原
-
You are here:
