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HIPK2 抗体 (AA 898-1051)

There is 1 publication for this product available. The 小鼠 单克隆 anti-HIPK2 antibody is suitable to detect HIPK2 in samples from 人. It has been validated for WB, IHC, IP, ICC 和 IF.
产品编号 ABIN2668288
发货至: 中国
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Quick Overview for HIPK2 抗体 (AA 898-1051) (ABIN2668288)

抗原

See all HIPK2 抗体
HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

适用

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宿主

  • 69
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小鼠

克隆类型

  • 46
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单克隆

标记

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This HIPK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

3E9
  • 抗原表位

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    AA 898-1051

    原理

    HIPK2 antibody (mAb) (Clone 3E9)

    纯化方法

    Protein G Chromatography

    免疫原

    This HIPK2 antibody was raised against a recombinant protein including amino acids 898-1051 of mouse HIPK2.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Isono, Nemoto, Li, Takada, Suzuki, Katsuki, Nakagawara, Koseki: "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." in: Molecular and cellular biology, Vol. 26, Issue 7, pp. 2758-71, (2006) (PubMed).

  • 抗原

    HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

    别名

    HIPK2

    背景

    HIPK2 (Homeodomain Interacting Protein Kinase 2) is a serine/threonine kinase present in the nucleus that interacts with homeodomain transcription factors and acts as a co-repressor of transcription. It inhibits cell growth, as well as promotes apoptosis through the phosphorylation and subsequent degradation of the anti-apoptotic factor CTBP1. HIPK2 also phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity.

    分子量

    130 kDa

    基因ID

    28996

    NCBI登录号

    NP_034563

    途径

    Cell Division Cycle
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