AGO1 抗体 (N-Term)
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北京 101111
Quick Overview for AGO1 抗体 (N-Term) (ABIN2668226)
抗原
See all AGO1 (EIF2C1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Ago1 antibody (mAb) (Clone 4B8)
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纯化方法
- Protein G Chromatography
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免疫原
- This Ago1 antibody was raised against a peptide from the N-terminus of human Argonaute 1 (Ago1) protein.
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亚型
- IgG2a
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anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) antibody
EIF2C1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (AA 27-56), (N-Term) antibodyEIF2C1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB18965 unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (AA 1-180) antibodyEIF2C1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (Internal Region) antibodyEIF2C1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (Internal Region) antibodyVerified EIF2C1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (AA 27-56) antibodyEIF2C1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (AA 251-400) antibodyEIF2C1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (N-Term) antibodyEIF2C1 适用: 人, 小鼠, 大鼠, 犬, 猴, 兔, 马, Cow, 豚鼠, Pig, 非洲爪蟾, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) antibodyEIF2C1 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB8080 unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (N-Term) antibodyEIF2C1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Identification of human microRNA targets from isolated argonaute protein complexes." in: RNA biology, Vol. 4, Issue 2, pp. 76-84, (2007) (PubMed).
: "Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells." in: EMBO reports, Vol. 8, Issue 11, pp. 1052-60, (2007) (PubMed).
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- AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
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别名
- Ago1
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背景
- The Argonaute family proteins (Ago1, Ago2, Ago3 and Ago4) are involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Binding of RISC can inhibit mRNA translation and results in the degradation of the mRNA through the action of Ago2-mediated target cleavage. Ago1 is non-essential for siRNA-directed target RNA cleavage but is needed for the production of mature miRNA that affects miRNA-directed RNA cleavage. Argonaute family proteins contain a PAZ and a PIWI domain.
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分子量
- 100 kDa
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基因ID
- 26523
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NCBI登录号
- NP_036331
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Transport, Regulation of Actin Filament Polymerization, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
抗原
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