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TIMP1 抗体

TIMP1 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal F31P2A5 unconjugated
产品编号 ABIN2666373
发货至: 中国
  • 抗原 See all TIMP1 抗体
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TIMP1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    F31P2A5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TIMP1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    别名
    TIMP-1 (TIMP1 产品)
    别名
    TIMP-1 antibody, TIMP1 antibody, DKFZp468A0912 antibody, CLGI antibody, EPA antibody, EPO antibody, HCI antibody, TIMP antibody, Timp antibody, Clgi antibody, TIMP metallopeptidase inhibitor 1 antibody, tissue inhibitor of metalloproteinase 1 antibody, TIMP1 antibody, Timp1 antibody
    背景
    TIMP-1 (Tissue inhibitor of metalloproteinase 1) is a glycoprotein that belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain, predicted molecular weight 23 kD. TIMP-1 forms complexes with matrix metalloproteinases (MMPs) and inhibits the proteolytic activity of these enzymes. High levels TIMP-1 protein has been found in several types of cancers including breast cancer and this increase associated with a poor patient prognosis. TIMP-1 has also been implicated in the inhibition of apoptosis, promotion of growth, and process of angiogenesis. TIMP-1 may be useful as a prognostic marker in combination with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1). Clone F31P2A5 has been shown to be useful for western blotting, immunohistochemistry and ELISA of human and monkey TIMP-1.
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