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TIMP1 抗体

This anti-TIMP1 antibody is a 小鼠 单克隆 antibody detecting TIMP1 in FACS. Suitable for 人 和 猴.
产品编号 ABIN2666373
发货至: 中国

Quick Overview for TIMP1 抗体 (ABIN2666373)

抗原

See all TIMP1 抗体
TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

适用

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人, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This TIMP1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

F31P2A5
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原

    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

    别名

    TIMP-1

    背景

    TIMP-1 (Tissue inhibitor of metalloproteinase 1) is a glycoprotein that belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain, predicted molecular weight 23 kD. TIMP-1 forms complexes with matrix metalloproteinases (MMPs) and inhibits the proteolytic activity of these enzymes. High levels TIMP-1 protein has been found in several types of cancers including breast cancer and this increase associated with a poor patient prognosis. TIMP-1 has also been implicated in the inhibition of apoptosis, promotion of growth, and process of angiogenesis. TIMP-1 may be useful as a prognostic marker in combination with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1). Clone F31P2A5 has been shown to be useful for western blotting, immunohistochemistry and ELISA of human and monkey TIMP-1.
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