SPI1 抗体
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北京 101111
Quick Overview for SPI1 抗体 (ABIN2666294)
抗原
See all SPI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity purified.
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亚型
- IgG1 kappa
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anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 16-170) antibody
SPI1 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal PU1-2146 unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 124-271) antibodySPI1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5C7 unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 124-271) antibodySPI1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 1-120) antibodySPI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (Internal Region) antibodyVerified SPI1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 1-122) antibodySPI1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 1-264) antibodySPI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 217-246) antibodySPI1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 20-70) antibodySPI1 适用: 人, 小鼠, 犬, Cow, 马, 猴 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 18-196) antibodySPI1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Upon receipt, store undiluted between 2°C and 8°C.
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- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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别名
- SPI1
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背景
- SPI1 is a transcription factor belonging to the E26-transformation-specific (Ets) family and is exclusively expressed in hematopoietic cells. SPI1 regulates cell fate decisions during differentiation of hematopoietic stem cells, which is crucial for the development of lymphoid and myeloid cell lineages. SPI1-deficient mice lack macrophages, neutrophils, and B lymphocytes, and they die before or shortly after birth. Abnormally regulated expression of SPI1 can lead to developmental defects as well as occurring malignancy. Overexpression of SPI1 blocks erythroid differentiation and inhibits cell death. Mice carrying a mutant SPI1 allele show decreased SPI1 expression and develop acute myeloid leukaemia (AML), suggesting the role of SPI1 in oncogenesis.
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途径
- Stem Cell Maintenance
抗原
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