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RAG2 抗体

RAG2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 3G4A26 unconjugated
产品编号 ABIN2666293
发货至: 中国
  • 抗原 See all RAG2 抗体
    RAG2 (Recombination Activating Gene 2 (RAG2))
    适用
    • 45
    • 13
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 40
    • 6
    小鼠
    克隆类型
    • 42
    • 4
    单克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAG2 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 13
    • 12
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purified.
    克隆位点
    3G4A26
    亚型
    IgG2b kappa
    Top Product
    Discover our top product RAG2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原
    RAG2 (Recombination Activating Gene 2 (RAG2))
    别名
    RAG2 (RAG2 产品)
    别名
    RAG-2 antibody, Rag-2 antibody, rag-2 antibody, zgc:136743 antibody, recombination activating 2 antibody, recombination activating gene 2 antibody, recombination activating gene 2 S homeolog antibody, RAG2 antibody, Rag2 antibody, rag2 antibody, rag2.S antibody
    背景
    During T cell and B cell development, RAG2 works together with RAG1 to induce DNA rearrangement and assembly of antigen receptor coding segments. Defects in RAG2 gene lead to the complete lack of mature T and B lymphocytes and result in severe combined immunodeficiency (SCID). RAG2 also functions in chromosome binding through its unique plant homeodomain (PHD). Sequestration of recombination signal sequences (RSS) within the nucleosome by RAG2 prevents access by the recombinase complex.
    途径
    Chromatin Binding, Production of Molecular Mediator of Immune Response
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