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IRF9 抗体

IRF9 适用: 人 FACS 宿主: 小鼠 Monoclonal 5A3A39 unconjugated
产品编号 ABIN2666230
发货至: 中国
  • 抗原 See all IRF9 抗体
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    适用
    • 48
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 43
    • 6
    • 1
    小鼠
    克隆类型
    • 45
    • 4
    单克隆
    标记
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF9 antibody is un-conjugated
    应用范围
    • 37
    • 15
    • 13
    • 13
    • 10
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    纯化方法
    Affinity purified.
    克隆位点
    5A3A39
    亚型
    IgG2b kappa
    Top Product
    Discover our top product IRF9 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted 2°C and 8°C.
  • 抗原
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    别名
    IRF9 (IRF9 产品)
    别名
    IRF-9 antibody, ISGF3 antibody, ISGF3G antibody, p48 antibody, zgc:92097 antibody, Irf-9 antibody, Isgf3g antibody, interferon regulatory factor 9 antibody, IRF9 antibody, irf9 antibody, Irf9 antibody
    背景
    IRF9 is a member of the IRF family of transcription factors and plays an important role in IFN signaling pathways and anti-viral immune responses. Type I and type III interferon stimulation induces phosphorylation and heterodimerization of STAT1 and STAT2. The activated STAT1:STAT2 heterodimer recruits IRF9 and forms a heterotrimeric complex termed IFN-stimulated gene factor 3 (ISGF3). The ISGF3 complex, in turn, translocates to the nucleus and transactivates IFN-inducible genes. The IRF9 protein in the ISGF3 complex is responsible for the recognition of IFN-stimulated response elements (ISRE). Mice lacking IRF9 fail to induce the expression of IFN regulated genes in response to type I interferon stimulation, indicating that IRF9 is crucial in mediating interferon signaling.
    途径
    JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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