电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IRF9 抗体

The 小鼠 单克隆 anti-IRF9 antibody is suitable to detect IRF9 in samples from 人. It has been validated for FACS.
产品编号 ABIN2666230
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IRF9 抗体 (ABIN2666230)

抗原

See all IRF9 抗体
IRF9 (Interferon Regulatory Factor 9 (IRF9))

适用

  • 59
  • 15
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 54
  • 6
  • 1
小鼠

克隆类型

  • 46
  • 14
单克隆

标记

  • 27
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IRF9 antibody is un-conjugated

应用范围

  • 47
  • 21
  • 15
  • 15
  • 13
  • 13
  • 13
  • 12
  • 7
  • 4
  • 3
Flow Cytometry (FACS)

克隆位点

5A3A39
  • 纯化方法

    Affinity purified.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store undiluted 2°C and 8°C.
  • 抗原

    IRF9 (Interferon Regulatory Factor 9 (IRF9))

    别名

    IRF9

    背景

    IRF9 is a member of the IRF family of transcription factors and plays an important role in IFN signaling pathways and anti-viral immune responses. Type I and type III interferon stimulation induces phosphorylation and heterodimerization of STAT1 and STAT2. The activated STAT1:STAT2 heterodimer recruits IRF9 and forms a heterotrimeric complex termed IFN-stimulated gene factor 3 (ISGF3). The ISGF3 complex, in turn, translocates to the nucleus and transactivates IFN-inducible genes. The IRF9 protein in the ISGF3 complex is responsible for the recognition of IFN-stimulated response elements (ISRE). Mice lacking IRF9 fail to induce the expression of IFN regulated genes in response to type I interferon stimulation, indicating that IRF9 is crucial in mediating interferon signaling.

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
You are here: