Nuclear Factor kappa B p50 (NFkB p50) 抗体
The 小鼠 单克隆 anti-Nuclear Factor kappa B p50 (NFkB p50) antibody is suitable to detect Nuclear Factor kappa B p50 (NFkB p50) in samples from 人. It has been validated for BCA.
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产品编号 ABIN2666083
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Nuclear Factor kappa B p50 (NFkB p50) 抗体 (ABIN2666083)
抗原
Nuclear Factor kappa B p50 (NFkB p50)
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Biochemical Assay (BCA)
克隆位点
4D1
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG1 kappa
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anti-Nuclear Factor kappa B p50 (NFkB p50) (N-Term) antibody
适用: 人 WB, ELISA, GS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. Final antibody concentration is 0.5 mg/mL.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Upon receipt, store between 2°C and 8°C.
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- Nuclear Factor kappa B p50 (NFkB p50)
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别名
- NF-B p50
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背景
- NF-κB/p50 (nuclear factor kappa light chain enhancer in B cells p50, NF-κB1) is a member of the Rel/dorsal family. This ubiquitously expressed nuclear protein is one subunit of the NF-kappa B complex consisting of a 65 kD transactivating subunit and a 50 kD DNA binding subunit. Both subunits are derived from larger precursor proteins. NF-κB acts as a transcriptional activator and was originally identified as an activator of kappa light chain in B cells. NF-κB/p50 is bound (with p65) to IκB inhibitor in cytoplasm in inactive form. Phosphorylation of IκB releases and NF- κB which goes to the nucleus to activate gene expression. NF-κB can be activated with LPS, TNF-α, phorbol ester, or IL-1. The 4D1 monoclonal antibody reacts with human NF-κB p50 and has been shown to be useful for Western blotting.
抗原
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