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CD3 抗体

This anti-CD3 antibody is a 小鼠 单克隆 antibody detecting CD3 in FACS 和 CyTOF. Suitable for 人.
产品编号 ABIN2666026
发货至: 中国

Quick Overview for CD3 抗体 (ABIN2666026)

抗原

See all CD3 抗体
CD3

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD3 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

克隆位点

UCHT1-3G8-MEM-188
  • 亚型

    IgG1, IgG2a
  • 应用备注

    This reagent is a combination of FITC conjugated UCHT1 and PE conjugated 3G8 and MEM-188 in optimal concentration for two-color flow cytometric analysis.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD3

    别名

    CD3

    背景

    CD3: UCHT1 antibody reacts with a combinatorial epitope of CD3ε, a 20 kD chain of the CD3/T-cell receptor (TCR) complex found on all mature T lymphocytes, NK-T cells and some thymocytes. CD16: 3G8 antibody reacts with CD16, a 50-65 kD transmembrane or a 48 kD GPI-anchored glycoprotein that is a member of the immunoglobulin superfamily. CD16 is expressed on NK cells, activated monocytes, macrophages, mast cells and neutrophils. CD56: MEM-188 antibody reacts with the 175 - 185 kD isoform of CD56, N-CAM (Neural Cell Adhesion Molecule), which is expressed on NK cells and a subset of CD3+ T cells. CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56.

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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