Leucine Peptidase 抗体
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北京 101111
Quick Overview for Leucine Peptidase 抗体 (ABIN2666017)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- This product is produced with low endotoxin and is supplied azide free.
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纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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储存液
- Azide free
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注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Leucine Peptidase
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别名
- LAP
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背景
- Transforming growth factor beta (TGF-β) is a cytokine that has critical functions in the immune response by regulating Treg and Th17 cell differentiation. TGF-β is first synthesized as pro-TGF-β which is then cleaved by furin proprotein convertase in the Golgi apparatus to produce a latent TGF-β complex. This complex consists of non-covalently associated dimers of the N-terminal region of pro-TGF-β (latency-associated peptide, LAP) and C-terminal region of pro-TGF-β (mature TGF-β). The latent-TGF-β has been found on the membrane of activated Treg cells, immature dendritic cells, megakaryocytes, and platelets.
抗原
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