CD300a 抗体
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北京 101111
Quick Overview for CD300a 抗体 (ABIN2665985)
抗原
See all CD300a (CD300A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- This product is produced with low endotoxin and is supplied azide free.
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纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
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亚型
- IgG2a kappa
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anti-CD300a (CD300A) (AA 18-180) antibody
CD300A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7H8E4 unconjugated
anti-CD300a (CD300A) (AA 18-180) antibodyCD300A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD300a (CD300A) antibody (PE)CD300A 适用: 人 FACS 宿主: 小鼠 Monoclonal P192 PE
anti-CD300a (CD300A) antibodyCD300A 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal MEM-260 unconjugated
anti-CD300a (CD300A) (Internal Region) antibodyCD300A 适用: 人 WB, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD300a (CD300A) (AA 1-299) antibodyCD300A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD300a (CD300A) antibody (APC)CD300A 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-260 APC
anti-CD300a (CD300A) antibody (PE)CD300A 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-260 PE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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储存液
- Azide free
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注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD300a (CD300A)
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别名
- CD300a
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背景
- CD300 receptors are a group of type I transmembrane proteins, which belong to the Ig superfamily. In mice, nine members have been reported with different nomenclature systems, such as myeloid-associated Ig-like receptor (MAIR), leukocyte mono-Ig-like receptor (LMIR), DC-derived Ig-like receptor (DIgR), and CMRF-35-like molecule (CLM). The CD300 Molecules act as either activating or inhibitory receptors through interactions with adaptor molecules, such as PAD12, DAP10, and FcRγ. CD300a is an inhibitory receptor that is mainly expressed on peripheral eosinophils, mast cells, neutrophils, dendritic cells, macrophages, and some B cells. Cross-linking CD300a by an antibody can induce phosphorylation of tyrosine residues in the cytoplasmic domain, which results in recruitment of phosphatases SHIP, SHP1 and SHP2 and inhibition of cell activation.
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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