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CD16 抗体

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in FACS 和 WB. Suitable for 人.
产品编号 ABIN2665954
发货至: 中国

Quick Overview for CD16 抗体 (ABIN2665954)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB)

克隆位点

3G8
  • 品牌

    Ultra-LEAF™

    交叉反应

    Chimpanzee, Baboon, Cynomolgus, 猕猴, Marmoset, Capuchin Monkey, Pigtailed Macaque, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.), Saguinus oedipus

    纯化方法

    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    储存液

    Azide free

    注意事项

    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD16

    别名

    CD16

    背景

    CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95 % homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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