IL-22 抗体 (Ala34)
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北京 101111
Quick Overview for IL-22 抗体 (Ala34) (ABIN2665496)
抗原
See all IL-22 (IL22) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Ala34
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交叉反应 （详细）
- In sandwich ELISA, less than 10 % cross-reactivity with recombinant mouse IL-22.
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纯化方法
- The antibody was purified by antigen affinity chromatography.
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免疫原
- Ala34-Isoleucin179 (Accession# NM_020525) was expressed in E. coli.
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亚型
- Ig Fraction, IgG
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anti-Interleukin 22 (IL22) (AA 35-179) antibody
IL22 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) antibodyIL22 适用: 人 WB, ELISA, IHC, Neut, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (C-Term) antibodyIL22 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 1-179) antibodyIL22 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) antibodyIL22 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
anti-Interleukin 22 (IL22) (AA 40-67) antibodyIL22 适用: 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IL-22 (IL22) (Interleukin 22 (IL22))
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别名
- IL-22
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背景
- IL-22 is a cytokine structurally related to IL-10. Originally identified as a murine gene induced by IL-9 in T and mast cells, IL-22 was initially designated ILTIF (IL-10-related T cell-derived inducible factor). IL-22 belongs to a family of cytokines with limited homology to IL-10, namely IL-10, IL-19, IL-20, IL-24, IL-26, and the IFN-λs, IL-28A, IL-28B and IL-29. Human IL-22 shares 79 % amino acid identity with murine IL-22 and 25 % identity with human IL-10. IL-22 biological activity is initiated by binding to a cell surface complex composed of IL-22R1 and IL-10R2 receptor chains. Activity is further regulated through interactions with the soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (sIL-22R1). Both chains of the IL-22R complex belong to the class II CRF. Two types of IL-22 binding receptors have been discovered, a membrane-bound receptor and a soluble receptor, both encoded by different genes. IL-22 is produced by Th17 cells and newly identified Th22 cells. It plays a critical role in mucosal immunity in addition to the deregulated inflammation observed in autoimmune diseases.
抗原
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