TCR V Beta8.1 抗体
This anti- antibody is a 大鼠 单克隆 antibody detecting in FACS. Suitable for 小鼠.
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Quick Overview for TCR V Beta8.1 抗体 (ABIN2665400)
抗原
TCR V Beta8.1
适用
小鼠
宿主
大鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS)
克隆位点
KJ16-133-18
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG2a kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- TCR V Beta8.1
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背景
- The TCR Vβ 8 family consists of three members, namely Vβ8.1, 8.2 and 8.3. KJ16-133.18 reacts with Vβ8.1, 8.2 only, but not Vβ8.3. Most mouse strains have about 20 % Vβ 8+ T cells in the periphery.However, C57BR, C57L, SJL, SWR (Tcra haplotype) and RIII strains (Tcrc haplotype) do not express Vβ8 due to a gene deletion at the Vβ 8 family loci.Other strains expressing endogenous super-antigen, such as Mls-1a have significant reduced number of Vβ 8.1 cells in the periphery.Exogenous superantigen, such as staphylococcal enterotoxin B, stimulates lymphocytes bearing Vβ 8 and selectively eliminate those T cells in vivo.
抗原
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