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SPHK1 抗体

This anti-SPHK1 antibody is a 小鼠 单克隆 antibody detecting SPHK1 in FACS. Suitable for 人 和 小鼠.
产品编号 ABIN2665362
发货至: 中国

Quick Overview for SPHK1 抗体 (ABIN2665362)

抗原

See all SPHK1 抗体
SPHK1 (Sphingosine Kinase 1 (SPHK1))

适用

  • 97
  • 42
  • 38
  • 9
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 88
  • 9
  • 1
小鼠

克隆类型

  • 82
  • 16
单克隆

标记

  • 58
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPHK1 antibody is un-conjugated

应用范围

  • 72
  • 40
  • 24
  • 22
  • 13
  • 13
  • 11
  • 11
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
Flow Cytometry (FACS)

克隆位点

1A5SC
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    SPHK1 (Sphingosine Kinase 1 (SPHK1))

    别名

    SPHK1

    背景

    SPHK1 is a lipid kinase that catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P) which is a key sphingolipid signaling molecule involved in cell growth, survival, differentiation, and motility. As an important regulator of ceramide, sphingosine, and S1P, SPHK1 plays important roles in immunological, inflammatory diseases, and cancer. SPHK1 is overexpressed in various types of cancers, and upregulation of SPHK1 has been associated with tumor angiogenesis and resistance to radiation and chemotherapy. Agents targeting the SPHK1 have the potential as therapeutics for cancer, immunological, and inflammatory disorders.

    途径

    VEGF Signaling
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