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RORC 抗体

This anti-RORC antibody is a Armenian Hamster 单克隆 antibody detecting RORC in WB. Suitable for 小鼠.
产品编号 ABIN2665349
发货至: 中国

Quick Overview for RORC 抗体 (ABIN2665349)

抗原

See all RORC 抗体
RORC (RAR-Related Orphan Receptor C (RORC))

适用

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小鼠

宿主

  • 92
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  • 1
Armenian Hamster

克隆类型

  • 95
  • 21
单克隆

标记

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This RORC antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RORg2
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    RORC (RAR-Related Orphan Receptor C (RORC))

    别名

    RORg

    背景

    RORγ (Retinoid-related orphan receptor gamma) belongs to the nuclear hormone receptor family, NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. RORγ has two isoforms: γ1 and γ2 (also referred to as RORγt). The RORγt differs from the RORγ1 isoform in that it lacks the amino terminus of RORγ1. RORγ1 contains 516 amino acids and RORγt contains 495 amino acids. RORγ1 has a molecular weight of approximately 58 kD. RORγ1 is highly expressed in thymus, kidney, liver, muscle, and brown fat but not in white fat tissue. RORγt is specifically expressed in only two cell populations, DP thymocytes and lymphoid tissue inducers (LTi). RORγ plays a critical role in control apoptosis during thymopoiesis and T cell homeostasis. RORγt is to regulate TCRα repertoire by virtue of its positive regulatory role on Bcl-x expression. RORγ is essential for lymph nodes and Peyers patch development.

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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