Pro-Major Basic Protein 1 抗体
This 小鼠 单克隆 antibody specifically detects Pro-Major Basic Protein 1 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN2665341
发货至:
中国
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中国
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北京 101111
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Quick Overview for Pro-Major Basic Protein 1 抗体 (ABIN2665341)
抗原
Pro-Major Basic Protein 1
适用
人
宿主
小鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS)
克隆位点
J175-7D4
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Pro-Major Basic Protein 1
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背景
- Pro-form of Major Basic Protein 1 (ProMBP1) is composed of a strongly acidic 90-residue propart and a highly basic mature portion of 117 residues. It is an extensively and very heterogeneously glycosylated proteoglycan. ProMBP1 is processed to 14 kD MBP1 by convertase during maturation and localized in cell granule core. The mature MBP1 is a cytotoxic protein. The mAb J175-7D4 binds ProMBP1 and intermediate ProMBP1, but not mature MBP1. It specifically stain basophils, does not stain eosinophils, granulocytes, and mast cells and can be used as a marker for human basophils.
抗原
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