mMCP-8 抗体
This anti- antibody is a 大鼠 单克隆 antibody detecting in FACS 和 IF. Suitable for 小鼠.
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Quick Overview for mMCP-8 抗体 (ABIN2665274)
抗原
mMCP-8
适用
小鼠
宿主
大鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF)
克隆位点
TUG8
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- mMCP-8
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背景
- MMCP-8 and its rat homologues, rMCP-8, -9, and -10, form a new group of mast cell/basophil proteases, which are more closely related to the T-cell granzymes and neutrophil cathepsin G than to the mast cell tryptases and chymases. mMCP-8 showed a high degree of homology with mouse granzyme B in the critical regions for determining substrate cleavage specificity. It preferentially cleaves after Asp residues. mMCP-8 mRNA is highly expressed in a mouse connective tissue MC-like tumor line. However, it could not be detected in mouse liver, intestine, lung or ears, indicating very low expression in normal tissues. A strong increase in mMCP-8 levels in the lungs can be detected in infected animals.
抗原
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