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IL-31 抗体

This anti-IL-31 antibody is a 大鼠 单克隆 antibody detecting IL-31 in BCA. Suitable for 小鼠.
产品编号 ABIN2665157
发货至: 中国

Quick Overview for IL-31 抗体 (ABIN2665157)

抗原

See all IL-31 (IL31) 抗体
IL-31 (IL31) (Interleukin 31 (IL31))

适用

  • 65
  • 14
  • 12
  • 5
  • 5
小鼠

宿主

  • 74
  • 22
大鼠

克隆类型

  • 68
  • 28
单克隆

标记

  • 48
  • 12
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-31 antibody is un-conjugated

应用范围

  • 53
  • 35
  • 35
  • 21
  • 17
  • 14
  • 14
  • 13
  • 9
  • 5
  • 4
  • 4
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  • 1
  • 1
Biochemical Assay (BCA)

克隆位点

1C2B07
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL-31 (IL31) (Interleukin 31 (IL31))

    别名

    IL-31

    背景

    IL-31, mainly produced by activated CD4+ T cells, is a helical cytokine belonging to the gp130/IL-6 cytokine family. IL-31 is closely related in structure to IL-6, IL-11, and IL-27. Binding of IL-31 to its receptor activates JAK/STAT, PI3K/AKT, and MAPK pathways. IL-31 acts on a broad range of immune and non-immune cells and thus possesses potential pleiotropic physiological functions, such as regulating hematopoiesis and immune response. Transgenic mice overexpressing IL-31 developed severe dermatitis, indicating that IL-31 is involved in skin immunity.
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