IL-27/IL-35 EBI3 Subunit (Dimer), (Heterodimer), (Monomer) 抗体
This 大鼠 单克隆 antibody specifically detects IL-27/IL-35 EBI3 Subunit in FACS. It exhibits reactivity toward 小鼠.
1 image
产品编号 ABIN2665152
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for IL-27/IL-35 EBI3 Subunit (Dimer), (Heterodimer), (Monomer) 抗体 (ABIN2665152)
抗原
IL-27/IL-35 EBI3 Subunit
适用
小鼠
宿主
大鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS)
克隆位点
J053B5
-
-
抗原表位
- Dimer, Heterodimer, Monomer
-
纯化方法
- The antibody was purified by affinity chromatography.
-
亚型
- IgG2a
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
-
- IL-27/IL-35 EBI3 Subunit
-
别名
- IL-27/IL-35 EBI3
-
背景
- EBI3 is an IL-12 p40-related protein that can heterodimerized with IL-12 p35 to form IL-35, or with an IL-12 p35-related protein, p28, to form IL-27. It is produced by antigen-presenting cells such as B cells, monocytes, and dendritic cells (DCs) following stimulation through TLR. It can regulate T cell differentiation and proliferation. Both IL-27 and IL-35 are anti-inflammatory cytokines that are able to inhibit Th17 generation, promote Th1 differentiation, increase cytolytic activity of CD8+ T cells, and impact B cell differentiation and immunoglobulin production. IL-35 is also involved in tumorigenesis and is a promising biomarker for assessing tumor progression and prognosis in clinical settings.
抗原
-
You are here:
