IL-27/IL-35 EBI3 Subunit (Dimer), (Heterodimer), (Monomer) 抗体
This anti- antibody is a 大鼠 单克隆 antibody detecting in FACS. Suitable for 小鼠.
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Quick Overview for IL-27/IL-35 EBI3 Subunit (Dimer), (Heterodimer), (Monomer) 抗体 (ABIN2665152)
抗原
IL-27/IL-35 EBI3 Subunit
适用
小鼠
宿主
大鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS)
克隆位点
J053B5
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抗原表位
- Dimer, Heterodimer, Monomer
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IL-27/IL-35 EBI3 Subunit
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别名
- IL-27/IL-35 EBI3
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背景
- EBI3 is an IL-12 p40-related protein that can heterodimerized with IL-12 p35 to form IL-35, or with an IL-12 p35-related protein, p28, to form IL-27. It is produced by antigen-presenting cells such as B cells, monocytes, and dendritic cells (DCs) following stimulation through TLR. It can regulate T cell differentiation and proliferation. Both IL-27 and IL-35 are anti-inflammatory cytokines that are able to inhibit Th17 generation, promote Th1 differentiation, increase cytolytic activity of CD8+ T cells, and impact B cell differentiation and immunoglobulin production. IL-35 is also involved in tumorigenesis and is a promising biomarker for assessing tumor progression and prognosis in clinical settings.
抗原
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