IL23 抗体
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北京 101111
Quick Overview for IL23 抗体 (ABIN2665148)
抗原
See all IL23 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG2b kappa
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anti-Interleukin 23 (IL23) (AA 101-196) antibody
IL23 适用: 人, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 (IL23) antibodyIL23 适用: 人 IHC, ELISA, Func 宿主: 小鼠 Monoclonal B-Z23 unconjugated
anti-Interleukin 23 (IL23) (C-Term) antibodyIL23 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IL23 (Interleukin 23 (IL23))
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别名
- IL-23
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背景
- Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12.IL-23 is secreted by activated macrophages and dendritic cells.Human and mouse p19 share 70 % aa sequence identity. The functional IL-23 receptor complex consists of two receptor subunits, a β1 subunit shared with the IL-12 receptor (IL-12R β1) and a β2-like subunit with STAT4 binding domain, termed the IL-23-specific receptor subunit (IL-23R).IL-23 has been shown to enhance IFN-γ production by memory T cells.Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the potent proinflammatory cytokine IL-17.IL-23 has been shown to be upregulated in certain autoimmune diseases and promote immunity in response to some viral and mycobacterial infections.
抗原
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