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IL23 抗体

This anti-IL23 antibody is a 小鼠 单克隆 antibody detecting IL23 in WB, IHC, IP 和 ICFC. Suitable for 人.
产品编号 ABIN2665145
发货至: 中国

Quick Overview for IL23 抗体 (ABIN2665145)

抗原

See all IL23 抗体
IL23 (Interleukin 23 (IL23))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL23 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Intracellular Flow Cytometry (ICFC)

克隆位点

HLT2736
  • 无交叉反应

    小鼠

    产品特性

    The HLT2736 clone recognizes human IL-23, a heterodimeric cytokine composed of the p40 subunit shared with IL-12 and a specific p19 subunit. This antibody recognizes heterodimeric IL-23, but does not react with the p40 subunit alone or recombinant IL-12(p70) when used as a capture antibody in ELISA. IL-23 is secreted by activated dendritic cells and macrophages and has been shown to enhance IFN-γ secretion by memory (CD45RO) T cells in an IL-2 dependent manner. IL-23 may also induce unique Th subset (designated ThIL-17) that secretes the cytokines IL-17, IL-6, TNF and low levels of IFN-γ. IL-23 has been shown to promote immunity to mycobacteria and has been shown to be upregulated in response to some viral infections and in psoriatic lesions. IL-23 binds to the IL-23 receptor comprised of a β1 subunit shared with the IL-12 receptor and IL-23-specific subunit. This antibody has been shown to be useful for Western blotting and immunohistochemistry using formalin-fixed, paraffin embedded tissues with (catalyzed signal amplification).

    纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL23 (Interleukin 23 (IL23))

    别名

    IL-23
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