IB-alpha 抗体
This 小鼠 单克隆 antibody specifically detects IB-alpha in FACS. It exhibits reactivity toward 人.
产品编号 ABIN2665062
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for IB-alpha 抗体 (ABIN2665062)
抗原
IB-alpha
适用
人
宿主
小鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS)
克隆位点
3D6C02
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交叉反应
- 小鼠
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交叉反应 （详细）
- Weakly reacts with mouse
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IB-alpha
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背景
- IκB-α is an inhibitory protein that binds to the NF-κB complex and retains this complex in the cytoplasm where it cannot activate transcription. Upon cellular stimulation, the IκB proteins are phosphorylated and degraded via the ubiquitin pathway allowing for nuclear translocation of NF-κB. The NF-κB complex can then bind DNA to activate gene expression of multiple proteins involved in inflammation, cellular proliferation, differentiation, and apoptosis.
抗原
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