HSP90 alpha/beta 抗体
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- 抗原 See all HSP90 alpha/beta products
- HSP90 alpha/beta (Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HSP90 alpha/beta antibody is un-conjugated
- 应用范围
- 请咨询
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- 3H3C27
- 亚型
- IgG2b kappa
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- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- HSP90 alpha/beta (Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta))
- 别名
- Hsp90alpha/beta (HSP90 alpha/beta 产品)
- 背景
- Hsp90 is one of the most abundant molecular chaperones. It modulates the stability and transport of a diverse set of critical factors, which include regulatory, metabolic, organizational, and signaling proteins. There are two major isoforms: α and β. In humans, the Hsp90β isoform is constitutively expressed, whereas the Hsp90α isoform is expressed under stress conditions. The Hsp90 dimer acts in concert with other chaperones and is regulated by a number of co-chaperones/accessory proteins. The upregulation of Hsp90 is associated with tumor progression, the invasion and formation of metastases, and the development of drug resistance. Therefore, Hsp90 has emerged as an important target for cancer treatment.
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