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HSP90 alpha/beta 抗体

HSP90 alpha/beta 适用: 人, 小鼠 宿主: 小鼠 Monoclonal 3H3C27 unconjugated
产品编号 ABIN2665053
发货至: 中国
  • 抗原 See all HSP90 alpha/beta products
    HSP90 alpha/beta (Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta))
    适用
    • 27
    • 21
    • 21
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 14
    • 10
    • 3
    小鼠
    克隆类型
    • 14
    • 12
    单克隆
    标记
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This HSP90 alpha/beta antibody is un-conjugated
    应用范围
    请咨询
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    3H3C27
    亚型
    IgG2b kappa
  • 限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    HSP90 alpha/beta (Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta))
    别名
    Hsp90alpha/beta (HSP90 alpha/beta 产品)
    背景
    Hsp90 is one of the most abundant molecular chaperones. It modulates the stability and transport of a diverse set of critical factors, which include regulatory, metabolic, organizational, and signaling proteins. There are two major isoforms: α and β. In humans, the Hsp90β isoform is constitutively expressed, whereas the Hsp90α isoform is expressed under stress conditions. The Hsp90 dimer acts in concert with other chaperones and is regulated by a number of co-chaperones/accessory proteins. The upregulation of Hsp90 is associated with tumor progression, the invasion and formation of metastases, and the development of drug resistance. Therefore, Hsp90 has emerged as an important target for cancer treatment.
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