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CX3CL1 抗体

CX3CL1 适用: 人 FACS 宿主: 小鼠 Monoclonal L393H11 unconjugated
产品编号 ABIN2664893
发货至: 中国
  • 抗原 See all CX3CL1 抗体
    CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 78
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    单克隆
    标记
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    This CX3CL1 antibody is un-conjugated
    应用范围
    • 72
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    L393H11
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CX3CL1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
    别名
    CX3CL1 (CX3CL1 产品)
    背景
    CX3CL1 is the only member of the CX3C chemokine family that is constitutively expressed in endothelial and epithelial cells, lymphocytes, neurons and microglial osteoblasts. CX3CL1 exists in two forms: as a membrane-anchored form of approximately 100 kD or as a shed 80-95 kD glycoprotein. The chemokine domain is roughly 8 kD, but it migrates at about 13 kD. Its membrane bound form promotes the firm adhesion of rolling leucocytes onto the vessel wall, while its soluble form serves as a potent chemoattractant for CX3CR1-expressing cells such as NK cells, CD14+ monocytes, cytotoxic effector T cells, B cells, neurons, microglia, smooth muscle cells, and tumor cells. The CX3CL1/CX3CR1 axis plays an important role in the pathogenesis of several inflammatory diseases such as allergic pathologies, rheumatoid arthritis, atherosclerosis and tumorigenesis.
    途径
    Synaptic Membrane
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