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ITGA2 抗体

ITGA2 适用: 人 FACS, IHC, CoSt 宿主: 小鼠 Monoclonal P1E6-C5 unconjugated
产品编号 ABIN2664741
发货至: 中国
  • 抗原 See all ITGA2 抗体
    ITGA2 (Integrin alpha 2 (ITGA2))
    适用
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    宿主
    • 78
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    小鼠
    克隆类型
    • 77
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    单克隆
    标记
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    This ITGA2 antibody is un-conjugated
    应用范围
    • 63
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Co-Stimulation (CoSt)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    P1E6-C5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ITGA2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    ITGA2 (Integrin alpha 2 (ITGA2))
    别名
    CD49b (ITGA2 产品)
    别名
    BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
    背景
    CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders.
    途径
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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