ITGA2 抗体
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- 抗原 See all ITGA2 抗体
- ITGA2 (Integrin alpha 2 (ITGA2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ITGA2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Co-Stimulation (CoSt)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- P1E6-C5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ITGA2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- ITGA2 (Integrin alpha 2 (ITGA2))
- 别名
- CD49b (ITGA2 产品)
- 背景
- CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders.
- 途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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